Agrp^{tm3(cre/ERT)Rpa}
Targeted Allele Detail

Summary

• Symbol: Agrp^{tm3(cre/ERT)Rpa}
• Name: agouti related neuropeptide; targeted mutation 3, Richard D Palmiter
• MGI ID: MGI:3527190
• Synonyms: Agrp-CreER, Agrp^tm3Rpa
• Gene: Agrp Location: Chr8:106293327-106306477 bp, - strand Genetic Position: Chr8, 53.04 cM, cytoband D1-D2
• Alliance: Agrp^{tm3(cre/ERT)Rpa} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:94338
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Agrp^{tm3(cre/ERT)Rpa} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Agrp (MGI:892013)

• Mutation details: Cre recombinase targeted to Agrp locus. Cre is fused to the estrogen receptor ligand-binding domain to allow activation by tamoxifen. (J:94338)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Agrp (mouse) Summary of all recombinase alleles driven by Agrp. Alliance mouse Agrp gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Agrp Mutation: 17 strains or lines available

References

• Original: J:94338 NIH Mouse Knockout Inventory, Information obtained from the NIH Mouse Knockout Inventory. MGI Direct Data Submission. 2004
• All: 2 reference(s)