Rflnb^tm1Sia
Targeted Allele Detail

Summary

• Symbol: Rflnb^tm1Sia
• Name: refilin B; targeted mutation 1, Shinichi Aizawa
• MGI ID: MGI:3528231
• Synonyms: Cfm1^-
• Gene: Rflnb Location: Chr11:75910020-75918608 bp, - strand Genetic Position: Chr11, 45.92 cM, cytoband B4
• Alliance: Rflnb^tm1Sia page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:95328
• Parent Cell Line: TT2 (ES Cell)
• Strain of Origin: (C57BL/6NCrlj x CBA/JNCrlj)F1

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A 2.4 kb sequence containing portions of exon 1 and exon 2 was replaced by a lacZ/neo cassette. RT-PCR analysis of brain did not detect gene product mRNA. (J:95328)

Expression

In Mice Carrying this Mutation:

4 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Rflnb Mutation: 11 strains or lines available

References

• Original: J:95328 Hirano M, et al., cfm is a novel gene uniquely expressed in developing forebrain and midbrain, but its null mutant exhibits no obvious phenotype. Gene Expr Patterns. 2005 Feb;5(3):439-44
• All: 2 reference(s)