Bag1^tm1Msd
Targeted Allele Detail

Summary

• Symbol: Bag1^tm1Msd
• Name: BCL2-associated athanogene 1; targeted mutation 1, Michael Sendtner
• MGI ID: MGI:3528234
• Synonyms: Bag1-, BAG-1^-, Bag1^tm1Urr
• Gene: Bag1 Location: Chr4:40936398-40948294 bp, - strand Genetic Position: Chr4, 20.67 cM, cytoband B1
• Alliance: Bag1^tm1Msd page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:95491
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• A neo replaced exons 1 and 2. Western blot demonstrated the lack of protein in mutant lungs. (J:101397)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Bag1 Mutation: 21 strains or lines available

References

• Original: J:95491 Gotz R, et al., BAG-1 haplo-insufficiency impairs lung tumorigenesis. BMC Cancer. 2004 Nov 24;4(1):85
• All: 5 reference(s)