Fgfr1^tm1Upir
Targeted Allele Detail

Summary

• Symbol: Fgfr1^tm1Upir
• Name: fibroblast growth factor receptor 1; targeted mutation 1, Ulla Pirvola
• MGI ID: MGI:3528437
• Synonyms: Fgfr1^flox
• Gene: Fgfr1 Location: Chr8:26008808-26067819 bp, + strand Genetic Position: Chr8, 14.12 cM
• Alliance: Fgfr1^tm1Upir page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:78879
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• LoxP sites were inserted to flank exons 8-15. (J:78879)

Disease models

Expression

In Mice Carrying this Mutation:	94 assay results
In Structures Affected by this Mutation:	12 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fgfr1 Mutation: 223 strains or lines available

References

• Original: J:78879 Pirvola U, et al., FGFR1 is required for the development of the auditory sensory epithelium. Neuron. 2002 Aug 15;35(4):671-80
• All: 37 reference(s)