Gpr84^tm1Lex
Targeted Allele Detail

Summary

• Symbol: Gpr84^tm1Lex
• Name: G protein-coupled receptor 84; targeted mutation 1, Lexicon Genetics
• MGI ID: MGI:3528887
• Gene: Gpr84 Location: Chr15:103216662-103219039 bp, - strand Genetic Position: Chr15, 58.88 cM
• Alliance: Gpr84^tm1Lex page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:186985
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The single coding exon was replaced with a lacZ/neo cassette. QRT-PCR confirmed the absence of transcript expression in the bone marrow. (J:186985)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Gpr84 Mutation: 33 strains or lines available

References

• Original: J:186985 Venkataraman C, et al., The G-protein coupled receptor, GPR84 regulates IL-4 production by T lymphocytes in response to CD3 crosslinking. Immunol Lett. 2005 Nov 15;101(2):144-53
• All: 2 reference(s)