Ppp1cc^tm1Lex
Targeted Allele Detail

Summary

• Symbol: Ppp1cc^tm1Lex
• Name: protein phosphatase 1 catalytic subunit gamma; targeted mutation 1, Lexicon Genetics
• MGI ID: MGI:3528932
• Synonyms: Ppp1cc^flx
• Gene: Ppp1cc Location: Chr5:122296341-122313336 bp, + strand Genetic Position: Chr5, 62.2 cM, cytoband F-G1
• Alliance: Ppp1cc^tm1Lex page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:203985
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Exons 2 and 3 were floxed.

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ppp1cc Mutation: 30 strains or lines available

References

• Original: J:203985 Sinha N, et al., Selective ablation of Ppp1cc gene in testicular germ cells causes oligo-teratozoospermia and infertility in mice. Biol Reprod. 2013 Nov;89(5):128
• All: 4 reference(s)