Rgs11^tm1Lex
Targeted Allele Detail

Summary

• Symbol: Rgs11^tm1Lex
• Name: regulator of G-protein signaling 11; targeted mutation 1, Lexicon Genetics
• MGI ID: MGI:3528953
• Gene: Rgs11 Location: Chr17:26421925-26430298 bp, + strand Genetic Position: Chr17, 13.07 cM
• Alliance: Rgs11^tm1Lex page

Rgs7^tm1Cjch/Rgs7^tm1Cjch Rgs11^tm1Lex/Rgs11^tm1Lex mice have no ERG b-waves and contain ultrastructural defects in the retinal outer plexiform layer

Show the 1 phenotype image(s) involving this allele.

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:103485
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Not Specified
• Mutation details: Coding exons 1 through 4 were targeted. Gene inactivation was confirmed by a lack of protein detected in immunoblot assays of retinal extracts. (J:103485, J:141120)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Rgs11 Mutation: 31 strains or lines available

Notes

See also, data as provided by Lexicon Genetics, Inc.

References

• Original: J:103485 Lexicon Genetics Inc, NIH initiative supporting placement of Lexicon Genetics, Inc. mice into public repositories. MGI Direct Data Submission. 2005
• All: 14 reference(s)