Slc17a5^tm1Lex
Targeted Allele Detail

Summary

• Symbol: Slc17a5^tm1Lex
• Name: solute carrier family 17 (anion/sugar transporter), member 5; targeted mutation 1, Lexicon Genetics
• MGI ID: MGI:3529082
• Synonyms: sialin^-
• Gene: Slc17a5 Location: Chr9:78443770-78495323 bp, - strand Genetic Position: Chr9, 43.65 cM
• Alliance: Slc17a5^tm1Lex page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:103485
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The first 104 nucleotides of the coding region were replaced with an IRES and beta-geo cassette. The absence of transcript expression was confirmed by RT-PCR analysis on liver extracts. The absence of protein expression was confirmed by immunhistochemistry on granule cell layer and hilar neurons of the dentate gyrus samples. (J:103485, J:158444)

Disease models

Expression

In Structures Affected by this Mutation:

7 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Slc17a5 Mutation: 37 strains or lines available

Notes

See also, data as provided by Lexicon Genetics, Inc.

References

• Original: J:103485 Lexicon Genetics Inc, NIH initiative supporting placement of Lexicon Genetics, Inc. mice into public repositories. MGI Direct Data Submission. 2005
• All: 6 reference(s)