Slc17a7^tm1Lex
Targeted Allele Detail

Summary

• Symbol: Slc17a7^tm1Lex
• Name: solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7; targeted mutation 1, Lexicon Genetics
• MGI ID: MGI:3529095
• Synonyms: Vglut1^-
• Gene: Slc17a7 Location: Chr7:44813373-44825566 bp, + strand Genetic Position: Chr7, 29.16 cM
• Alliance: Slc17a7^tm1Lex page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:103485
• Parent Cell Line: Lex-1 (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Coding exon 1 was targeted. A 72 bp genomic fragment starting with the ATG start codon in exon 1 was replaced with an IRES lacZ/MC1neo selection cassette. Transcript is absent in homozygous mice and protein was shown to be absent by Western blot analysis. (J:103485, J:174414)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Slc17a7 Mutation: 40 strains or lines available

Notes

See also, data as provided by Lexicon Genetics, Inc.

References

• Original: J:103485 Lexicon Genetics Inc, NIH initiative supporting placement of Lexicon Genetics, Inc. mice into public repositories. MGI Direct Data Submission. 2005
• All: 3 reference(s)