B3gnt2^{Gt(OST237555)Lex}
Gene trapped Allele Detail

Summary

• Symbol: B3gnt2^{Gt(OST237555)Lex}
• Name: UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2; gene trap OST237555, Lexicon Genetics
• MGI ID: MGI:3529146
• Synonyms: B3gnt2^Gt(neo)58Lex, beta3GnT2^-
• Gene: B3gnt2 Location: Chr11:22784739-22810336 bp, - strand Genetic Position: Chr11, 14.22 cM
• Alliance: B3gnt2^{Gt(OST237555)Lex} page

Mutation origin

• Mutant Cell Line: OST237555
• Germline Transmission: Earliest citation of germline transmission: J:125556
• Parent Cell Line: Lex-1 (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector
• Mutation details: The gene trap vector VICTR20 containing an IRES-betageo cassette and a PGK-puromycin cassette was inserted into the intronic sequence between exons 1 and 2. Insertion of the gene trap vector was confirmed by PCR. (J:125556)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any B3gnt2 Mutation: 156 strains or lines available

References

• Original: J:125556 Togayachi A, et al., Polylactosamine on glycoproteins influences basal levels of lymphocyte and macrophage activation. Proc Natl Acad Sci U S A. 2007 Oct 2;104(40):15829-34
• All: 1 reference(s)