Ccl25^tm1Lex
Targeted Allele Detail

Summary

• Symbol: Ccl25^tm1Lex
• Name: C-C motif chemokine ligand 25; targeted mutation 1, Lexicon Genetics
• MGI ID: MGI:3529266
• Synonyms: LEXKO-473
• Gene: Ccl25 Location: Chr8:4375210-4410020 bp, + strand Genetic Position: Chr8, 2.01 cM
• Alliance: Ccl25^tm1Lex page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:172753
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Coding exons 2 and 3 were targeted (NCBI accession NM_009138.1). Disruption of the target gene was confirmed by Southern hybridization analysis. (J:82809)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Ccl25 Mutation: 40 strains or lines available

References

• Original: J:172753 Desanti GE, et al., Clonal analysis reveals uniformity in the molecular profile and lineage potential of CCR9(+) and CCR9(-) thymus-settling progenitors. J Immunol. 2011 May 1;186(9):5227-35
• All: 2 reference(s)