P2rx7^tm1Lex
Targeted Allele Detail

Summary

• Symbol: P2rx7^tm1Lex
• Name: purinergic receptor P2X, ligand-gated ion channel, 7; targeted mutation 1, Lexicon Genetics
• MGI ID: MGI:3529296
• Gene: P2rx7 Location: Chr5:122781974-122829495 bp, + strand Genetic Position: Chr5, 62.5 cM, cytoband F
• Alliance: P2rx7^tm1Lex page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:103485
• Parent Cell Line: Lex-1 (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A 1496 bp fragment encoding exons 2 and 3 was replaced with a lacZ/neoselection cassette via homologous recombination. (J:103485, J:145020)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any P2rx7 Mutation: 54 strains or lines available

Notes

See also, data as provided by Lexicon Genetics, Inc.

References

• Original: J:103485 Lexicon Genetics Inc, NIH initiative supporting placement of Lexicon Genetics, Inc. mice into public repositories. MGI Direct Data Submission. 2005
• All: 8 reference(s)