Cia30^RIIIS/J
QTL Variant Detail

Summary

• QTL variant: Cia30^RIIIS/J
• Name: collagen induced arthritis QTL 30; RIIIS/J
• MGI ID: MGI:3529501
• QTL: Cia30 Location: unknown Genetic Position: Chr15, Syntenic

Variant origin

• Strain of Specimen: RIIIS/J

Variant description

• Allele Type: QTL
• Mutation: Undefined
• This allele confers resistance to collagen induced arthritis compared to B10.RIII. (J:95848)
• Inheritance: Recessive

Notes

Interaction between Cia30 and Cia5 on mouse Chromosome 3 affects late phase arthritis severity in male and female animals.

This allele confers CIA resistance when the Cia5 locus is homozygous for B10.RIII alleles.

References

• Original: J:95848 Karlsson J, et al., Genetic interactions in Eae2 control collagen-induced arthritis and the CD4+/CD8+ T cell ratio. J Immunol. 2005 Jan 1;174(1):533-41
• All: 2 reference(s)