Sirt3^{Gt(OST341297)Lex}
Gene trapped Allele Detail

Summary

• Symbol: Sirt3^{Gt(OST341297)Lex}
• Name: sirtuin 3; gene trap OST341297, Lexicon Genetics
• MGI ID: MGI:3529767
• Synonyms: Sirt3^{Gt(neo)218Lex}
• Gene: Sirt3 Location: Chr7:140443579-140462222 bp, - strand Genetic Position: Chr7, 86.07 cM, cytoband F4
• Alliance: Sirt3^{Gt(OST341297)Lex} page

Mutation origin

• Mutant Cell Line: OST341297
• Germline Transmission: Earliest citation of germline transmission: J:103485
• Parent Cell Line: Lex-1 (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector
• Mutation details: Retroviral insertion occurred in the intron preceding coding exon 1. RT-PCR analysis revealed that the transcript was absent in the homozygous mutant mice. (J:103485)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  OST341297	CG629301 ; (MGI Seq Detail)	3' RACE	Chr7:140443694-140445092 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  5 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Sirt3 Mutation: 32 strains or lines available

Notes

See also, data as provided by Lexicon Genetics, Inc.

References

• Original: J:103485 Lexicon Genetics Inc, NIH initiative supporting placement of Lexicon Genetics, Inc. mice into public repositories. MGI Direct Data Submission. 2005
• All: 17 reference(s)