Uchl5^{Gt(OST447189)Lex}
Gene trapped Allele Detail

Summary

• Symbol: Uchl5^{Gt(OST447189)Lex}
• Name: ubiquitin carboxyl-terminal esterase L5; gene trap OST447189, Lexicon Genetics
• MGI ID: MGI:3529781
• Synonyms: Uch37^-, Uchl5^{Gt(neo)226Lex}
• Gene: Uchl5 Location: Chr1:143653010-143683204 bp, + strand Genetic Position: Chr1, 62.54 cM, cytoband F
• Alliance: Uchl5^{Gt(OST447189)Lex} page

Uchl5^{Gt(OST447189)Lex}/Uchl5^{Gt(OST447189)Lex} embryos show defects in brain development

Show the 1 phenotype image(s) involving this allele.

Mutation origin

• Mutant Cell Line: OST447189
• Germline Transmission: Earliest citation of germline transmission: J:166694
• Parent Cell Line: Lex-1 (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector
• The gene trap vector inserted downstream of the exon containing the translation start site. (J:166694)

Expression

In Structures Affected by this Mutation:

5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Uchl5 Mutation: 26 strains or lines available

References

• Original: J:166694 Al-Shami A, et al., Regulators of the proteasome pathway, Uch37 and Rpn13, play distinct roles in mouse development. PLoS One. 2010;5(10):e13654
• All: 1 reference(s)