Arhgap12^{Gt(OST237375)Lex}
Gene trapped Allele Detail

Summary

• Symbol: Arhgap12^{Gt(OST237375)Lex}
• Name: Rho GTPase activating protein 12; gene trap OST237375, Lexicon Genetics
• MGI ID: MGI:3529984
• Synonyms: Arhgap12^{Gt(neo)294Lex}
• Gene: Arhgap12 Location: Chr18:6024448-6136102 bp, - strand Genetic Position: Chr18, 4.46 cM, cytoband A1
• Alliance: Arhgap12^{Gt(OST237375)Lex} page

Mutation origin

• Mutant Cell Line: OST237375
• Germline Transmission: Earliest citation of germline transmission: J:94338
• Parent Cell Line: Lex-1 (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector
• Mutation details: Retroviral insertion occurred upstream of the first coding exon (NM_029277). RT-PCR analysis revealed that the transcript was absent in the homozygous mutant mice. (J:82809)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  OST237375	CG587604 ; (MGI Seq Detail)	3' RACE	Chr18:6111835-6112199 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  15 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Arhgap12 Mutation: 48 strains or lines available

References

• Original: J:94338 NIH Mouse Knockout Inventory, Information obtained from the NIH Mouse Knockout Inventory. MGI Direct Data Submission. 2004
• All: 3 reference(s)