Rnf19a^{Gt(OST244733)Lex}
Gene trapped Allele Detail

Summary

• Symbol: Rnf19a^{Gt(OST244733)Lex}
• Name: ring finger protein 19A; gene trap OST244733, Lexicon Genetics
• MGI ID: MGI:3530036
• Synonyms: Dorfin^-, Rnf19a^{Gt(neo)330Lex}
• Gene: Rnf19a Location: Chr15:36240080-36283293 bp, - strand Genetic Position: Chr15, 14.46 cM
• Alliance: Rnf19a^{Gt(OST244733)Lex} page

Mutation origin

• Mutant Cell Line: OST244733
• Germline Transmission: Earliest citation of germline transmission: J:250032
• Parent Cell Line: Lex-1 (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector
• Mutation details: The gene trap cassette inserted into the intron between exon 2 and exon 3 of the gene. RT-PCR and quantitative PCR (qPCR) analyses revealed absence of mRNA expression in both the cortex and hippocampus of homozygous mutant mice. In situ hybridization confirmed that mRNA signals are almost undetectable in mutant brain. (J:250032)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  OST244733	CG590851 ; (MGI Seq Detail)	3' RACE	Chr15:36254601-36254674 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  1 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Rnf19a Mutation: 31 strains or lines available

References

• Original: J:94338 NIH Mouse Knockout Inventory, Information obtained from the NIH Mouse Knockout Inventory. MGI Direct Data Submission. 2004
• All: 3 reference(s)