Zfand5^{Gt(OST223460)Lex}
Gene trapped Allele Detail

Summary

• Symbol: Zfand5^{Gt(OST223460)Lex}
• Name: zinc finger, AN1-type domain 5; gene trap OST223460, Lexicon Genetics
• MGI ID: MGI:3530039
• Synonyms: Zfand5^{Gt(neo)331Lex}, Znf216^lex
• Gene: Zfand5 Location: Chr19:21249642-21264204 bp, + strand Genetic Position: Chr19, 14.32 cM
• Alliance: Zfand5^{Gt(OST223460)Lex} page

Mutation origin

• Mutant Cell Line: OST223460
• Germline Transmission: Earliest citation of germline transmission: J:105931
• Parent Cell Line: Lex-1 (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector
• Mutation details: Gene trap vector VICTR48, containing a neomycin and PGK-BTK, was inserted into intron 1. Absence of transcript and protein was confirmed by Northern and Western blot analysis, respectively. (J:105931)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  OST223460	CG582357 ; (MGI Seq Detail)	3' RACE	Chr19:21253878-21257069 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  22 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Zfand5 Mutation: 22 strains or lines available

References

• Original: J:105931 Hishiya A, et al., A novel ubiquitin-binding protein ZNF216 functioning in muscle atrophy. EMBO J. 2006 Feb 8;25(3):554-64
• All: 2 reference(s)