Npl^{Gt(OST15553)Lex}
Gene trapped Allele Detail

Summary

• Symbol: Npl^{Gt(OST15553)Lex}
• Name: N-acetylneuraminate pyruvate lyase; gene trap OST15553, Lexicon Genetics
• MGI ID: MGI:3530042
• Synonyms: Npl^{Gt(IRESBetageo)332Lex}
• Gene: Npl Location: Chr1:153378762-153425460 bp, - strand Genetic Position: Chr1, 65.38 cM, cytoband G2
• Alliance: Npl^{Gt(OST15553)Lex} page

Mutation origin

• Mutant Cell Line: OST15553
• Germline Transmission: Earliest citation of germline transmission: J:103485
• Parent Cell Line: Lex-1 (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector
• Mutation details: Retroviral insertion occurred in the intron between exons 10 and 11. RT-PCR analysis revealed that the transcript was absent in homozygous mice. (J:103485)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  OST15553	CG482452 ; (MGI Seq Detail)	3' RACE	Chr1:153378849-153384895 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  38 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 1 line available
• Carrying any Npl Mutation: 38 strains or lines available

Notes

See also, data as provided by Lexicon Genetics, Inc.

References

• Original: J:103485 Lexicon Genetics Inc, NIH initiative supporting placement of Lexicon Genetics, Inc. mice into public repositories. MGI Direct Data Submission. 2005
• All: 3 reference(s)