Srsf1^tm1.1Xdfu
Targeted Allele Detail

Summary

• Symbol: Srsf1^tm1.1Xdfu
• Name: serine and arginine-rich splicing factor 1; targeted mutation 1.1, Xiang-Dong Fu
• MGI ID: MGI:3530159
• Synonyms: ASF/SF2^-
• Gene: Srsf1 Location: Chr11:87938199-87944581 bp, + strand Genetic Position: Chr11, 52.4 cM
• Alliance: Srsf1^tm1.1Xdfu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:96039
• Parent Cell Line: J1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele is produced from Sfrs1^tm1Xdfu through cre recombinase in the oocyte resulting in deletion of exons 2 - 4 in the germline. (J:96039)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Srsf1 Mutation: 26 strains or lines available

References

• Original: J:96039 Xu X, et al., ASF/SF2-regulated CaMKIIdelta alternative splicing temporally reprograms excitation-contraction coupling in cardiac muscle. Cell. 2005 Jan 14;120(1):59-72
• All: 1 reference(s)