Bag3^{Gt(OST16086)Lex}
Gene trapped Allele Detail

Summary

• Symbol: Bag3^{Gt(OST16086)Lex}
• Name: BCL2-associated athanogene 3; gene trap OST16086, Lexicon Genetics
• MGI ID: MGI:3530294
• Synonyms: bag3^-, Bag3^{Gt(IRESBetageo)423Lex}
• Gene: Bag3 Location: Chr7:128125340-128148705 bp, + strand Genetic Position: Chr7, 70.26 cM
• Alliance: Bag3^{Gt(OST16086)Lex} page

Mutation origin

• Mutant Cell Line: OST16086
• Germline Transmission: Earliest citation of germline transmission: J:112361
• Parent Cell Line: Lex-1 (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector
• Immunoblot confirmed the absense of protein in these mutants.
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  OST16086	CG482810 ; (MGI Seq Detail)	3' RACE	Chr7:128147312-128147672 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  7 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Bag3 Mutation: 31 strains or lines available

References

• Original: J:112361 Homma S, et al., BAG3 deficiency results in fulminant myopathy and early lethality. Am J Pathol. 2006 Sep;169(3):761-73
• All: 6 reference(s)