Elovl6^{Gt(OST222498)Lex}
Gene trapped Allele Detail

Summary

• Symbol: Elovl6^{Gt(OST222498)Lex}
• Name: ELOVL fatty acid elongase 6; gene trap OST222498 Lexicon Genetics
• MGI ID: MGI:3530353
• Synonyms: Elovl6^{Gt(neo)444Lex}
• Gene: Elovl6 Location: Chr3:129326035-129432144 bp, + strand Genetic Position: Chr3, 58.05 cM
• Alliance: Elovl6^{Gt(OST222498)Lex} page

Mutation origin

• Mutant Cell Line: OST222498
• Germline Transmission: Earliest citation of germline transmission: J:82809
• Parent Cell Line: Lex-1 (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector
• Mutation details: Retroviral insertion ocurred between coding exons 1 and 2 (NM_130450.1). RT-PCR analysis revealed that the transcript was absent in the homozygous mutant mice. (J:82809)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  OST222498	CG581849 ; (MGI Seq Detail)	3' RACE	Chr3:129398696-129426894 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  259 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Elovl6 Mutation: 252 strains or lines available

Notes

Response to mutant cell line used in J:130031 and J:227324 (12/31/15). Dear Dr. Tomczuk, Thank you for your contact to us. Sorry for my late reply. The ID of our mutant cell line is OST222498. If I can be of any further assistance, please do not hesitate to contact me. Best regards, Takashi Takashi Matsuzaka, Ph. D Associate Professor Department of Endocrinology and Metabolism, Faculty of Medicine, University of Tsukuba 1-1-1 Tennodai, Tsukuba, Ibaraki, Japan, 305-8575 E-mail: t-matsuz@md.tsukuba.ac.jp HP: http://www.u-tsukuba-endocrinology.jp/

References

• Original: J:82809 European Mouse Mutant Archive, Information obtained from the European Mouse Mutant Archive (EMMA). Unpublished. 2003-2013
• All: 12 reference(s)