Peg12^tm1Brn
Targeted Allele Detail

Summary

• Symbol: Peg12^tm1Brn
• Name: paternally expressed 12; targeted mutation 1, Anton Berns
• MGI ID: MGI:3530465
• Synonyms: Frat3^lacZ
• Gene: Peg12 Location: Chr7:62111619-62114258 bp, - strand Genetic Position: Chr7, 34.38 cM
• Alliance: Peg12^tm1Brn page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:96034
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Most of the coding sequence was replaced by a cassette containing a lacZ reporter gene and hygromycin selection gene. Expression of lacZ was driven by the endogenous promoter. (J:96034)

Disease models

Expression

In Mice Carrying this Mutation:

18 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Peg12 Mutation: 10 strains or lines available

References

• Original: J:96034 van Amerongen R, et al., Frat is dispensable for canonical Wnt signaling in mammals. Genes Dev. 2005 Feb 15;19(4):425-30
• All: 2 reference(s)