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Gpr65tm1Witt
Targeted Allele Detail
Summary
Symbol: Gpr65tm1Witt
Name: G-protein coupled receptor 65; targeted mutation 1, Owen N Witte
MGI ID: MGI:3530470
Synonyms: TDAG8-
Gene: Gpr65  Location: Chr12:98234894-98242903 bp, + strand  Genetic Position: Chr12, 49.84 cM
Alliance: Gpr65tm1Witt page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:96112
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsMost of exon 2 was replaced with an IRES-EGFP and a floxed neo. The absence of transcript expression was confirmed by RT-PCR on spleen and thymus extracts. (J:144144)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Gpr65 Mutation:  22 strains or lines available
References
Original:  J:96112 Radu CG, et al., Differential proton sensitivity of related G protein-coupled receptors T cell death-associated gene 8 and G2A expressed in immune cells. Proc Natl Acad Sci U S A. 2005 Feb 1;102(5):1632-7
All:  13 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory