Gpr65^tm1Witt
Targeted Allele Detail

Summary

• Symbol: Gpr65^tm1Witt
• Name: G-protein coupled receptor 65; targeted mutation 1, Owen N Witte
• MGI ID: MGI:3530470
• Synonyms: TDAG8^-
• Gene: Gpr65 Location: Chr12:98234894-98242903 bp, + strand Genetic Position: Chr12, 49.84 cM
• Alliance: Gpr65^tm1Witt page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:96112
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129X1/SvJ

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Most of exon 2 was replaced with an IRES-EGFP and a floxed neo. The absence of transcript expression was confirmed by RT-PCR on spleen and thymus extracts. (J:144144)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Gpr65 Mutation: 22 strains or lines available

References

• Original: J:96112 Radu CG, et al., Differential proton sensitivity of related G protein-coupled receptors T cell death-associated gene 8 and G2A expressed in immune cells. Proc Natl Acad Sci U S A. 2005 Feb 1;102(5):1632-7
• All: 14 reference(s)