Tg(Atp4b-TAg)#Jig
Transgene Detail

Summary

• Symbol: Tg(Atp4b-TAg)#Jig
• Name: transgene insertion, Jeffrey I Gordon
• MGI ID: MGI:3530509
• Synonyms: Atp4b-SV40 TAg, Atp4b-TAg, Tg(Atp4b-TAg)1Jig
• Transgene: Tg(Atp4b-TAg)#Jig Location: unknown
• Alliance: Tg(Atp4b-TAg)#Jig page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: The SV40 large T antigen was cloned downstream of a segment encoding the murine Apt4b promoter (spanning nt -1035 to +24). Expression of this transgene was expected in the progenitors of acid-producing parietal cells. This allele record represents the pooling of two unnamed founder lines that were reported to exhibit similar phenotypes. (J:89240)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:89240 Syder AJ, et al., A transgenic mouse model of metastatic carcinoma involving transdifferentiation of a gastric epithelial lineage progenitor to a neuroendocrine phenotype. Proc Natl Acad Sci U S A. 2004 Mar 30;101(13):4471-6
• All: 1 reference(s)