Pdgfc^{Gt(OST91573)Lex}
Gene trapped Allele Detail

Summary

• Symbol: Pdgfc^{Gt(OST91573)Lex}
• Name: platelet-derived growth factor, C polypeptide; gene trap OST91573, Lexicon Genetics
• MGI ID: MGI:3530825
• Synonyms: Pdgfc^{Gt(neo)572Lex}
• Gene: Pdgfc Location: Chr3:80943723-81121347 bp, + strand Genetic Position: Chr3, 35.73 cM
• Alliance: Pdgfc^{Gt(OST91573)Lex} page

Mutation origin

• Mutant Cell Line: OST91573
• Germline Transmission: Earliest citation of germline transmission: J:103485
• Parent Cell Line: Lex-1 (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Gene trapped (Null/knockout)
• Mutation: Insertion of gene trap vector
• Mutation details: Retroviral insertion occurred between the first and second coding exons. RT-PCR analysis revealed that transcript was absent in the homozygous mice. (J:171883)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  OST91573	CG522256 ; (MGI Seq Detail)	3' RACE	Chr3:81048743-81049031 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  10 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 3 strains available Cell Lines: 1 line available
• Carrying any Pdgfc Mutation: 35 strains or lines available

Notes

See also, data as provided by Lexicon Genetics, Inc.

References

• Original: J:103485 Lexicon Genetics Inc, NIH initiative supporting placement of Lexicon Genetics, Inc. mice into public repositories. MGI Direct Data Submission. 2005
• All: 3 reference(s)