Map4k5^{Gt(OST218153)Lex}
Gene trapped Allele Detail

Summary

• Symbol: Map4k5^{Gt(OST218153)Lex}
• Name: mitogen-activated protein kinase kinase kinase kinase 5; gene trap OST218153, Lexicon Genetics
• MGI ID: MGI:3530833
• Synonyms: Map4k5^{Gt(neo)580Lex}
• Gene: Map4k5 Location: Chr12:69850531-69939937 bp, - strand Genetic Position: Chr12, 28.94 cM, cytoband C3
• Alliance: Map4k5^{Gt(OST218153)Lex} page

Mutation origin

• Mutant Cell Line: OST218153
• Germline Transmission: Earliest citation of germline transmission: J:82809
• Parent Cell Line: Lex-1 (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector
• Mutation details: Retroviral insertion ocurred between coding exons 1 and 2 (NM_024275.1). RT-PCR analysis revealed that the transcript was absent in the homozygous mutant mice. (J:82809)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  OST218153	CG579636 ; (MGI Seq Detail)	3' RACE	Chr12:69899482-69903637 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  26 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Map4k5 Mutation: 75 strains or lines available

References

• Original: J:82809 European Mouse Mutant Archive, Information obtained from the European Mouse Mutant Archive (EMMA). Unpublished. 2003-2013
• All: 2 reference(s)