Cacybp^{GT(OST39970)Lex}
Gene trapped Allele Detail

Summary

• Symbol: Cacybp^{GT(OST39970)Lex}
• Name: calcyclin binding protein; gene trap OST39970, Lexicon Genetics
• MGI ID: MGI:3530884
• Synonyms: Cacybp^{GT(IRESBetageo)616Lex}, SIP^-
• Gene: Cacybp Location: Chr1:160029937-160040445 bp, - strand Genetic Position: Chr1, 69.61 cM, cytoband H1
• Alliance: Cacybp^{GT(OST39970)Lex} page

Mutation origin

• Mutant Cell Line: OST39970
• Germline Transmission: Earliest citation of germline transmission: J:110899
• Parent Cell Line: Lex-1 (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector
• Mutation details: The VICTR20 gene trap vector inserted into intron 1 of the locus. Northern blot confirmed absence of transcript in mutants. (J:110899)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  OST39970	CG498557 ; (MGI Seq Detail)	3' RACE	Chr1:160031109-160036164 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  116 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Cacybp Mutation: 93 strains or lines available

References

• Original: J:110899 Fukushima T, et al., Critical function for SIP, a ubiquitin E3 ligase component of the beta-catenin degradation pathway, for thymocyte development and G1 checkpoint. Immunity. 2006 Jan;24(1):29-39
• All: 2 reference(s)