Gabarap^{Gt(OST31915)Lex}
Gene trapped Allele Detail

Summary

• Symbol: Gabarap^{Gt(OST31915)Lex}
• Name: gamma-aminobutyric acid receptor associated protein; gene trap OST31915, Lexicon Genetics
• MGI ID: MGI:3530887
• Synonyms: GABARAP^-, Gabarap^{Gt(IRESBetageo)618Lex}
• Gene: Gabarap Location: Chr11:69882196-69885775 bp, + strand Genetic Position: Chr11, 42.95 cM, cytoband B4
• Alliance: Gabarap^{Gt(OST31915)Lex} page

Mutation origin

• Mutant Cell Line: OST31915
• Germline Transmission: Earliest citation of germline transmission: J:104314
• Parent Cell Line: Lex-1 (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector
• Mutation details: A gene trap vector was inserted 345 bp upstream of exon 1. Western blot failed to detect protein in mutant brain fractions. (J:104314)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  OST31915	CG493547 ; (MGI Seq Detail)	3' RACE	Chr11:69883206-69885448 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  5 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gabarap Mutation: 22 strains or lines available

References

• Original: J:104314 O'Sullivan GA, et al., GABARAP is not essential for GABA receptor targeting to the synapse. Eur J Neurosci. 2005 Nov;22(10):2644-8
• All: 4 reference(s)