Mgll^{Gt(OST113734)Lex}
Gene trapped Allele Detail

Summary

• Symbol: Mgll^{Gt(OST113734)Lex}
• Name: monoglyceride lipase; gene trap OST113734, Lexicon Genetics
• MGI ID: MGI:3530905
• Synonyms: MAGL^-, Mgll^-, Mgll^Gt1(neo), Mgll^{Gt(neo)625Lex}
• Gene: Mgll Location: Chr6:88701397-88805342 bp, + strand Genetic Position: Chr6, 39.51 cM
• Alliance: Mgll^{Gt(OST113734)Lex} page

Mutation origin

• Mutant Cell Line: OST113734
• Germline Transmission: Earliest citation of germline transmission: J:94338
• Parent Cell Line: Lex-1 (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector
• Mutation details: The gene trap vector inserted upstream of the catalytic exon 4. The absence of protein expression was confirmed by activity-based protein profiling of brain membrane proteosomes and mass spectrometry-based proteomics. (J:165274)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  OST113734	CG531233 ; (MGI Seq Detail)	3' RACE	Chr6:88786316-88800222 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  2 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Expression

In Mice Carrying this Mutation:	9 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Mgll Mutation: 31 strains or lines available

References

• Original: J:94338 NIH Mouse Knockout Inventory, Information obtained from the NIH Mouse Knockout Inventory. MGI Direct Data Submission. 2004
• All: 14 reference(s)