Fuz^{Gt(OSTGST001398)Lex}
Gene trapped Allele Detail

Summary

• Symbol: Fuz^{Gt(OSTGST001398)Lex}
• Name: fuzzy planar cell polarity protein; gene trap OSTGST001398, Lexicon Genetics
• MGI ID: MGI:3531090
• Synonyms: Fuz^Gt1(neo), Fuz^Gt652Lex
• Gene: Fuz Location: Chr7:44545517-44552053 bp, + strand Genetic Position: Chr7, 28.99 cM, cytoband B2
• Alliance: Fuz^{Gt(OSTGST001398)Lex} page

Craniofacial defects in Fuz^{Gt(OSTGST001398)Lex}/Fuz^{Gt(OSTGST001398)Lex} mice

Show the 4 phenotype image(s) involving this allele.

Mutation origin

• Mutant Cell Line: OSTGST001398
• Germline Transmission: Earliest citation of germline transmission: J:158243
• Parent Cell Line: Lex-1 (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector
• The gene trap vector inserted into exon 2. (J:158243)

Expression

In Mice Carrying this Mutation:	2 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	26 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fuz Mutation: 23 strains or lines available

References

• Original: J:158243 Gray RS, et al., The planar cell polarity effector Fuz is essential for targeted membrane trafficking, ciliogenesis and mouse embryonic development. Nat Cell Biol. 2009 Oct;11(10):1225-32
• All: 8 reference(s)