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Tg(tetO-MYC)1Lach
Transgene Detail
Summary
Symbol: Tg(tetO-MYC)1Lach
Name: transgene insertion 1, Lewis A Chodosh
MGI ID: MGI:3531157
Synonyms: Tg(MYC)1lach, TOM, TRE-Myc
Transgene: Tg(tetO-MYC)1Lach  Location: unknown  
Alliance: Tg(tetO-MYC)1Lach page
Transgene
origin
Strain of Origin:  FVB
Transgene
description
Transgene Type:    Transgenic (Inducible, Inserted expressed sequence)
Inducer:    doxycycline/tetracycline
Mutation:    Insertion
 
Tg(tetO-MYC)1Lach expresses 1 gene
 
Mutation detailsThis transgene contains exons 2 and 3 of the human v-myc avian myelocytomatosis viral oncogene homolog gene and and regulatory elements from the bacterial tetracycline-resistance operon. (J:67498)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 2 anatomical structure(s)
Tumor Data
List all tumor models in MMHCdb carrying Tg(tetO-MYC)1Lach
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:67498 D'Cruz CM, et al., c-MYC induces mammary tumorigenesis by means of a preferred pathway involving spontaneous Kras2 mutations. Nat Med. 2001 Feb;7(2):235-9
All:  22 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory