Rb(12.Ts17¹⁶65Dn)2Cje
Allele Detail

Summary

• Symbol: Rb(12.Ts17¹⁶65Dn)2Cje
• Name: Robertsonian translocation, Chr 12 and T17¹⁶Dn, Charles J Epstein 2
• MGI ID: MGI:3531161
• Synonyms: Rb2Cje, Ts2, Ts2Cje, Ts(Rb(12.17¹⁶))2Cje
• Gene: Rb(12.Ts17¹⁶65Dn)2Cje Location: unknown

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Not Applicable
• Mutation: Translocation
• Mutation details: A female mouse with 40 chromosomes and 41 arms was detected by chromosome analysis of progeny from T17¹⁶65Dn mice. This mouse had a unique biarmed chromosome that appeared to be the result of a fusion between chromosome 12 and the marker chromosome T(17¹⁶)65Dn.

Disease models

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Rb(12.Ts17 16 65Dn)2Cje Mutation: 1 strain or line available

References

• Original: J:96650 Villar AJ, et al., Identification and characterization of a new Down syndrome model, Ts[Rb(12.1716)]2Cje, resulting from a spontaneous Robertsonian fusion between T(171)65Dn and mouse chromosome 12. Mamm Genome. 2005 Feb;16(2):79-90
• All: 16 reference(s)