Cia26^RIIIS/J
QTL Variant Detail

Summary

• QTL variant: Cia26^RIIIS/J
• Name: collagen induced arthritis QTL 26; RIIIS/J
• MGI ID: MGI:3531545
• QTL: Cia26 Location: unknown Genetic Position: Chr15, Syntenic

Variant origin

• Strain of Specimen: RIIIS/J

Variant description

• Allele Type: QTL
• Inheritance: Not Specified

Notes

Homozygous RIIIS/J-derived alleles at Cia26 interact with B10.RIII-derived alleles at Cia30 to promote severe CIA and increase disease incidence in female animals.

References

• Original: J:95848 Karlsson J, et al., Genetic interactions in Eae2 control collagen-induced arthritis and the CD4+/CD8+ T cell ratio. J Immunol. 2005 Jan 1;174(1):533-41
• All: 1 reference(s)