H2-Ob^vic1
Spontaneous Allele Detail

Summary

• Symbol: H2-Ob^vic1
• Name: histocompatibility 2, O region beta locus; virus infectivity controller 1
• MGI ID: MGI:3573873
• Gene: H2-Ob Location: Chr17:34457879-34464882 bp, + strand Genetic Position: Chr17, 17.98 cM
• Alliance: H2-Ob^vic1 page

Mutation origin

• Strain of Origin: I/LnJ

Mutation description

• Allele Type: Spontaneous (Null/knockout)
• Mutation: Nucleotide substitutions
• Mutation details: This I/LnJ loss-of-function variant has eight nucleotide substitutions in the 5-prime and four nucleotide substitutions in the 3-prime non-coding regions and four coding mutations that cause the amino acid substitutions S128N, V148I, L167H, and E239K. (J:254532)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any H2-Ob Mutation: 24 strains or lines available

References

• Original: J:60602 Golovkina TV, A novel mechanism of resistance to mouse mammary tumor virus infection. J Virol. 2000 Mar;74(6):2752-9
• All: 7 reference(s)