Tg(Tyr-cre)1Lru
Transgene Detail

Summary

• Symbol: Tg(Tyr-cre)1Lru
• Name: transgene insertion 1, Lionel Larue
• MGI ID: MGI:3573939
• Synonyms: Tyr::Cre, Tyr-CreA, Tyr::CreA
• Transgene: Tg(Tyr-cre)1Lru Location: unknown Genetic Position: ChrX, Syntenic
• Alliance: Tg(Tyr-cre)1Lru page

Transgene origin

• Strain of Origin: C57BL/6 x DBA/2

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Tyr-cre)1Lru expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Tyr (MGI:98880)

• Mutation details: A mouse tyrosinase promoter drives the expression of Cre recombinase. By crossing to a reporter strain, Cre activity was detected in skin melanoblasts from E11.5 and in skin, eyes, brain and peripheral nerves. (J:84391)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Tyr (mouse) Summary of all recombinase alleles driven by Tyr. Comparative matrix view of recombinase activities Alliance mouse Tyr gene page

Disease models

Expression

In Mice Carrying this Mutation:

4 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:84391 Delmas V, et al., Cre-mediated recombination in the skin melanocyte lineage. Genesis. 2003 Jun;36(2):73-80
• All: 43 reference(s)