Itgb4^tm2Son
Targeted Allele Detail

Summary

• Symbol: Itgb4^tm2Son
• Name: integrin beta 4; targeted mutation 2, Arnoud Sonnenberg
• MGI ID: MGI:3573958
• Synonyms: Beta4^flox
• Gene: Itgb4 Location: Chr11:115865556-115899238 bp, + strand Genetic Position: Chr11, 80.91 cM
• Alliance: Itgb4^tm2Son page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:96543
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: Exons 1b-5 were left flanked with loxP sites following transient cre expression and the excision of a floxed neo. (J:96543)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Itgb4 Mutation: 107 strains or lines available

References

• Original: J:96543 Raymond K, et al., Keratinocytes display normal proliferation, survival and differentiation in conditional {beta}4-integrin knockout mice. J Cell Sci. 2005 Mar 1;118(Pt 5):1045-60
• All: 12 reference(s)