Msmb^tm1Xuan
Targeted Allele Detail

Summary

• Symbol: Msmb^tm1Xuan
• Name: beta-microseminoprotein; targeted mutation 1, Jim W Xuan
• MGI ID: MGI:3574429
• Synonyms: PSP-KIMAP
• Gene: Msmb Location: Chr14:31863980-31880284 bp, + strand Genetic Position: Chr14, 19.4 cM, cytoband B
• Alliance: Msmb^tm1Xuan page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:96884
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted
• Mutation: Insertion
• Mutation details: SV40 Tag (2.7 kb, both large T and small t antigens) and a neomycin gene were inserted at the middle of the first exon via homologous recombination. (J:96884)

Disease models

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Tumor Data

List all tumor models in MMHCdb carrying Msmb^tm1Xuan

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Msmb Mutation: 11 strains or lines available

References

• Original: J:96884 Duan W, et al., Knockin of SV40 Tag oncogene in a mouse adenocarcinoma of the prostate model demonstrates advantageous features over the transgenic model. Oncogene. 2005 Feb 24;24(9):1510-24
• All: 8 reference(s)