Gct6^SJL
QTL Variant Detail

Summary

• QTL variant: Gct6^SJL
• Name: granulosa cell tumorigenesis 6; SJL
• MGI ID: MGI:3574518
• QTL: Gct6 Location: ChrX:47179121-129764756 bp Genetic Position: ChrX, Syntenic

Variant origin

• Strain of Specimen: SJL

Variant description

• Allele Type: QTL
• Mutation: Undefined
• This allele confers susceptibility to granulosa cell turmor formation compared to SWR. (J:87114)

Notes

This allele interacts with a closely linked locus named Gct4. SJL-derived alleles at Gct6 enhance the tumor susceptible effect of Gct4^SJL.

References

• Original: J:87114 Dorward AM, et al., High-resolution genetic map of X-linked juvenile-type granulosa cell tumor susceptibility genes in mouse. Cancer Res. 2003 Dec 1;63(23):8197-202
• All: 1 reference(s)