Slc26a4^loop
Chemically induced Allele Detail

Summary

• Symbol: Slc26a4^loop
• Name: solute carrier family 26, member 4; loop
• MGI ID: MGI:3574673
• Synonyms: ABE028
• Gene: Slc26a4 Location: Chr12:31569826-31609968 bp, - strand Genetic Position: Chr12, 13.53 cM, cytoband B1
• Alliance: Slc26a4^loop page

Gross malformation of the vestibular gravity receptor in Slc26a4^loop/Slc26a4^loop mice

Show the 4 phenotype image(s) involving this allele.

Mutation origin

• Strain of Origin: C3HeB/FeJ

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: A C to T transition (C1223T) causes a serine (aromatic) to phenylalanine (polar) amino acid substitution at position 408. (J:68708, J:163655)

Expression

In Structures Affected by this Mutation:

13 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slc26a4 Mutation: 39 strains or lines available

References

• Original: J:163655 Dror AA, et al., Calcium oxalate stone formation in the inner ear as a result of an Slc26a4 mutation. J Biol Chem. 2010 Jul 9;285(28):21724-35
• All: 4 reference(s)