Tg(Col1a1-cre)1Bek
Transgene Detail

Summary

• Symbol: Tg(Col1a1-cre)1Bek
• Name: transgene insertion 1, Barbara E Kream
• MGI ID: MGI:3574761
• Synonyms: 3.6-Col1a1-Cre, Col 3.6-Cre, Col3.6-Cre
• Transgene: Tg(Col1a1-cre)1Bek Location: unknown
• Alliance: Tg(Col1a1-cre)1Bek page

Pkd1^tm2Ggg/Pkd1^tm2Ggg Tg(Col1a1-cre)1Bek/0 mice develop polycystic pancreas and kidney

Show the 6 phenotype image(s) involving this allele.

Transgene origin

• Strain of Origin: CD-1

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Col1a1-cre)1Bek expression driven by 1 gene
  Transgene expression driven by:
  

  Organism

  Driver Gene

  Homolog in Mouse

  Note

  rat

  Col1a1 (29393)

  Col1a1

  (MGI:88467)

• Mutation details: 3.6 kb of the rat Col1a1 promoter was used to drive cre expression in both osseous and non-osseous tissues. No line numbers were assigned. Line 1 is designated as representative of the 3.6 kb promoter. (J:97142)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Col1a1 (rat) Summary of all recombinase alleles driven by Col1a1. Comparative matrix view of recombinase activities Alliance rat Col1a1 gene page

Disease models

Expression

In Mice Carrying this Mutation:

20 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:97142 Liu F, et al., Expression and activity of osteoblast-targeted Cre recombinase transgenes in murine skeletal tissues. Int J Dev Biol. 2004 Sep;48(7):645-53
• All: 31 reference(s)