Bmpr2^tm1.1Enl
Targeted Allele Detail

Summary

• Symbol: Bmpr2^tm1.1Enl
• Name: bone morphogenetic protein receptor type 2; targeted mutation 1.1, En Li
• MGI ID: MGI:3574812
• Synonyms: Bmpr2^f, BMPR-II^2loxP
• Gene: Bmpr2 Location: Chr1:59802721-59917240 bp, + strand Genetic Position: Chr1, 30.44 cM, cytoband C2
• Alliance: Bmpr2^tm1.1Enl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:97109
• Parent Cell Line: J1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: Bmpr2^tm1Enl were crossed with EIIa-Cre mediated recombination was used to leave exons 4 and 5 flanked with loxP sites. (J:97109)

Disease models

Expression

In Mice Carrying this Mutation:	2 assay results
In Structures Affected by this Mutation:	6 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Bmpr2 Mutation: 46 strains or lines available

References

• Original: J:97109 Beppu H, et al., Generation of a floxed allele of the mouse BMP type II receptor gene. Genesis. 2005 Mar;41(3):133-7
• All: 36 reference(s)