Il17rd^tm1Sla
Targeted Allele Detail

Summary

• Symbol: Il17rd^tm1Sla
• Name: interleukin 17 receptor D; targeted mutation 1 Siew-Lan Ang
• MGI ID: MGI:3574925
• Synonyms: Sef^neo
• Gene: Il17rd Location: Chr14:26760990-26829243 bp, + strand Genetic Position: Chr14, 16.09 cM
• Alliance: Il17rd^tm1Sla page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:97106
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 5-12 were replaced with a PGK-neo cassette. These exons encode the functional cytoplasmic domain. (J:97106)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Il17rd Mutation: 85 strains or lines available

References

• Original: J:97106 Lin W, et al., Synergistic activity of Sef and Sprouty proteins in regulating the expression of Gbx2 in the mid-hindbrain region. Genesis. 2005 Mar;41(3):110-5
• All: 1 reference(s)