Grm8^tm1En
Targeted Allele Detail

Summary

• Symbol: Grm8^tm1En
• Name: glutamate receptor, metabotropic 8; targeted mutation 1, Eric S Nisenbaum
• MGI ID: MGI:3574927
• Synonyms: mGlu8^-
• Gene: Grm8 Location: Chr6:27275120-28135094 bp, - strand Genetic Position: Chr6, 11.97 cM, cytoband A3
• Alliance: Grm8^tm1En page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:97019
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• A neo replaced the sequence encoding amino acids 24-101. (J:97019)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Grm8 Mutation: 68 strains or lines available

References

• Original: J:97019 Zhai J, et al., Modulation of lateral perforant path excitatory responses by metabotropic glutamate 8 (mGlu8) receptors. Neuropharmacology. 2002 Aug;43(2):223-30
• All: 6 reference(s)