Gabrg2^tm1Dc
Targeted Allele Detail

Summary

• Symbol: Gabrg2^tm1Dc
• Name: gamma-aminobutyric acid type A receptor, subunit gamma 2; targeted mutation 1, D W Cope
• MGI ID: MGI:3574929
• Synonyms: gamma2F77I
• Gene: Gabrg2 Location: Chr11:41801030-41891684 bp, - strand Genetic Position: Chr11, 24.8 cM
• Alliance: Gabrg2^tm1Dc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:97175
• Parent Cell Line: E14.1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Not Specified)
• Mutations: Insertion, Nucleotide substitutions
• Mutation details: A targeting vector was designed to create an F77I substitution in exon 4. An FRT flanked neo was inserted downstream of the exon and subsequently deleted via Flp mediated recombination. (J:97175)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gabrg2 Mutation: 41 strains or lines available

References

• Original: J:97175 Cope DW, et al., Abolition of zolpidem sensitivity in mice with a point mutation in the GABAA receptor gamma2 subunit. Neuropharmacology. 2004 Jul;47(1):17-34
• All: 2 reference(s)