Tg(Sftpc-cre)1Blh
Transgene Detail

Summary

• Symbol: Tg(Sftpc-cre)1Blh
• Name: transgene insertion 1, Brigid L Hogan
• MGI ID: MGI:3574949
• Synonyms: Cre^Sftpc, Sftpc-cre, SPC-Cre
• Transgene: Tg(Sftpc-cre)1Blh Location: unknown
• Alliance: Tg(Sftpc-cre)1Blh page

Transgene origin

• Strain of Origin: (C57BL/6 x DBA/2)F2

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Sftpc-cre)1Blh expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  Not Specified	Sftpc

• Mutation details: The Sftpc promoter was cloned upstream of the rabbit beta-globin intron 2, followed by cre recombinase, an NLS and the beta-globin polyA signal. Sftpc is active in the lung endoderm beginning at E10.5. (J:91317, J:97215)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Sftpc (species not specified) Summary of all recombinase alleles driven by Sftpc. Comparative matrix view of recombinase activities

Disease models

Expression

In Mice Carrying this Mutation:	179 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	2 anatomical structure(s)

Tumor Data

List all tumor models in MMHCdb carrying Tg(Sftpc-cre)1Blh

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:91317 Okubo T, et al., Hyperactive Wnt signaling changes the developmental potential of embryonic lung endoderm. J Biol. 2004;3(3):11
• All: 68 reference(s)