T(16;17)43H
Radiation induced Allele Detail

Summary

• Symbol: T(16;17)43H
• Name: reciprocal translocation, Chr 16 and 17, Harwell 43
• MGI ID: MGI:3574967
• Synonyms: T43, Ts43H
• Gene: T(16;17)43H Location: unknown Genetic Position: Chr16, cytoband A

Mutation origin

• Strain of Origin: (C3H/HeH x 101/H)F1

Mutation description

• Allele Type: Radiation induced
• Mutation: Translocation
• Mutation details: This chromosome is a result of a reciprocal translocation with one breakpoint located within the centromeric heterochromatin of Chr16, and the other located in the B3 band of Chr17. In conjunction with a normal Chr16 and two normal Chr17s, the presence of this mutation results in segmental trisomy of the proximal 30 Mb of Chr17, which includes over 310 known genes, and monosomy for the tip of centromeric heterochromatin of Chr16. (J:97039)

Disease models

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any T(16;17)43H Mutation: 1 strain or line available

References

• Original: J:34742 Lyon MF, et al., Autosomal translocations causing male sterility and viable aneuploidy in the mouse. Cytogenetics. 1966;5:335-54
• All: 6 reference(s)