Ptprm^tm1Mfbg
Targeted Allele Detail

Summary

• Symbol: Ptprm^tm1Mfbg
• Name: protein tyrosine phosphatase receptor type M; targeted mutation 1, Martijn F B G Gebbink
• MGI ID: MGI:3575002
• Synonyms: RPTPmu^-, RPTPmu-LacZ^-
• Gene: Ptprm Location: Chr17:66973942-67661452 bp, - strand Genetic Position: Chr17, 37.88 cM
• Alliance: Ptprm^tm1Mfbg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:97231
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: LacZ and a hygro cassette were inserted at the ATG such that betagalactosidase was expressed by the endogenous regulatory sequences. Part of the first exon was deleted. (J:97231)

Expression

In Mice Carrying this Mutation:	89 assay results
In Structures Affected by this Mutation:	2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ptprm Mutation: 62 strains or lines available

References

• Original: J:97231 Koop EA, et al., Receptor protein tyrosine phosphatase mu expression as a marker for endothelial cell heterogeneity; analysis of RPTPmu gene expression using LacZ knock-in mice. Int J Dev Biol. 2003 Jun;47(5):345-54
• All: 4 reference(s)