Tg(Acr-EGFP)1Osb
Transgene Detail

Summary

• Symbol: Tg(Acr-EGFP)1Osb
• Name: transgene insertion 1, Research Institute for Microbial Diseases, Osaka University
• MGI ID: MGI:3575110
• Synonyms: Acr3-EGFP, Tg(acro3-EGFP)01Osb, Tg(NCAG-EGFP)CZ-001-FM260Osb
• Transgene: Tg(Acr-EGFP)1Osb Location: unknown
• Alliance: Tg(Acr-EGFP)1Osb page

Transgene origin

• Strain of Origin: (C57BL/6 x C3H)F1

Transgene description

• Transgene Type: Transgenic (Reporter)
• Mutation: Insertion
• Mutation details: Transgenic mice were made with a series of constructs in which the acrosin promoter and varying lengths of coding sequence were fused to the EGFP gene. The transgenic line entered here includes the Acr promoter, signal peptide, and N-terminal peptide. This is one of six such lines. Another construct fused only the Acr promoter to EGFP (3 lines). The third construct was made up of the Acr promoter, and signal peptide fused to EGFP (4 lines). The fourth construct was made up of the Acr promoter, signal peptide and a mutated N-terminal peptide in which there is an N to Q substitution (6 lines). (J:97291)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:97291 Nakanishi T, et al., Real-time observation of acrosomal dispersal from mouse sperm using GFP as a marker protein. FEBS Lett. 1999 Apr 23;449(2-3):277-83
• All: 30 reference(s)