Htr7^tm1Mrg
Targeted Allele Detail

Summary

• Symbol: Htr7^tm1Mrg
• Name: 5-hydroxytryptamine (serotonin) receptor 7; targeted mutation 1, M R Guscott
• MGI ID: MGI:3575513
• Synonyms: 5-HT7^-
• Gene: Htr7 Location: Chr19:35936134-36034907 bp, - strand Genetic Position: Chr19, 30.3 cM
• Alliance: Htr7^tm1Mrg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:97159
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: A targeting vector was designed to delete exon 1. In situ hybridization confirmed the absence of expression in mutants. (J:97159)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Htr7 Mutation: 33 strains or lines available

References

• Original: J:97159 Guscott MR, et al., The hypothermic effect of 5-CT in mice is mediated through the 5-HT7 receptor. Neuropharmacology. 2003 Jun;44(8):1031-7
• All: 2 reference(s)